Study: How Omega-3 in Pregnancy is Linked to Childhood Obesity
Adequate intake of omega-3 fatty acids during pregnancy may lower the risk of childhood obesity by 32%, according to new research from Harvard Medical School.
The study, published in American Journal of Clinical Nutrition, examined the relationship between the type of fat a mother consumed at mid-pregnancy and whether her child was obese at age 3 – determined by body mass index (BMI) and skinfold measurements.
The researchers, led by Dr. Emily Oken, associate professor in the department of population medicine, reported that enhanced maternal-fetal omega-3 status was associated with lower childhood obesity.
“We examined the extent to which prenatal omega-3 and omega-6 PUFA concentrations were associated with childhood adiposity,” wrote Onken and her colleagues.
“A higher ratio of cord plasma omega-6 to omega-3 polyunsaturated fatty acids (PUFAs) was associated with higher subscapular and triceps [skinfold thicknesses] and odds of obesity,” they said.
Omega-3 and obesity
The consumption of omega-3 fatty acids, most notably EPA and DHA, is associated with several health benefits, including improving of lipid metabolism, preventing coronary heart diseases, and reducing inflammatory responses. In addition, omega-3s have been suggested to reduce fat levels in animals fed a high-fat diet.
Onken and her colleagues explained that a low intake of omega-3 fatty acids, found mainly in fish and seafood, in addition to a presence of large amounts of omega-6s has been suggested to be a risk factor in the development of obesity.
Previous research in animals found that such imbalances in the types of fatty acids in the diet, promotes the development of fat tissue. However, the authors noted that very few studies have investigated these effects in human populations.
Study details
Onken and her colleagues reported that around one fifth expectant mothers ate more than 2 fish meals per week at mid-pregnancy, however only about half of these women achieved the recommend intake of DHA of 200 mg per day.
The authors said that such an observation suggests although pregnant women ate fish, they did not consume enough of the species known to contain high amounts of DHA, such as salmon, tuna, and mackerel.
Only 3% of pregnant women in the study were found to consume the recommended intake of 200 mg/day of DHA in the last month of pregnancy. Onken and her team noted that this is the time when large amounts of DHA are transferred from the mother to the infant to support brain development.
The research team then calculated the odds for obesity in the offspring at age 3 according to the mother’s omega-3 fatty acid intake and the level of omega-6s and omega-3s in cord blood at delivery.
Onken and her co-workers reported the odds of obesity in 3-year-olds were between 2 and 4 times higher when cord blood had a high ratio of omega-6 to omega-3 fatty acids.
In contrast, the odds of obesity were 32% lower when maternal consumption of omega-3s was high or if the ratio of omega-3 to omega-6 was at close to recommended levels.
The Harvard research team noted that the study is the first indications from human data that low intakes of omega-3s in the presence of large amounts of omega-6s during pregnancy might affect the chance of obesity in the offspring.
“These findings need to be confirmed by others. It will also be important to demonstrate that making deliberate changes to a woman’s fat intake during pregnancy has desirable effects on weight and fatness in children,” they added.
Source: American Journal of Clinical Nutrition
Volume 93, Issue 4, Pages 780-788, doi: 10.3945/?ajcn.110.005801
“Prenatal fatty acid status and child adiposity at age 3 y: results from a US pregnancy cohort”
Authors: S. M Donahue, S.L Rifas-Shiman, D.R. Gold, Z.E Jouni, M.W Gillman, E. Oken.
Even More Reason to Manage Weight, Cholesterol & High Blood Pressure
NON
-ALCOHOLIC LIVER DISEASE POISED FOR EPIDEMIC STATUS
A study projects that new cases of non-alcoholic fatty liver disease (NAFLD) will soon push this type of chronic liver disease (CLD), one of the major worldwide causes of morbidity and mortality, into epidemic status. (NAFLD is a spectrum of disease in people who do not drink alcohol excessively and ranges from excess fat in the liver, to fat in combination with inflammation and liver cell injury, to cirrhosis and its complications, particularly liver cancer.)
During the first cycle of statistics studied (1988-1994), NAFLD accounted for 46.8 percent of all CLD; but by the third cycle studied (2005-2008), NAFLD accounted for 75.1 percent of all CLD cases.
At this rate, prevalence will increase a further 50% by 2030. The researchers concluded that it is urgent to alert the public to the importance of exercise, proper diet and avoiding obesity, all of which lower NAFLD risk.
The study may also suggest a need to prevent the underlying causes of NAFLD, which in addition to obesity, include: metabolic syndrome, insulin resistance associated with diabetes, high cholesterol and high blood pressure. This not-yet-published study was presented in Berlin today, April 2, 2011, at the International Liver Congress.
10 Tactics for Overcoming Sugar Addiction
This was such a great article, we are posting it from Rodale.com.
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10 Tactics for Overcoming Sugar Addiction
By Jeffrey Rossman, Ph.D., Rodale.com
Are you addicted to sugar?
When I ask that question, most people attending my weight-management lectures raise their hand. Addiction to sugar is stronger for some people than others, but the truth is sugar is a powerfully addictive substance. If you’ve overindulged in cookies, candy, cake, or ice cream—and who hasn’t, at some point—you know its seductive pull. Food manufacturers bank on it when they load sugar into soft drinks, breakfast cereal, soups, salad dressings, spaghetti sauce, energy bars, and even catsup.
Addiction to sugar is probably more common than you think. Americans consume an average of 20 to 30 teaspoons (about ½ cup!) daily of this substance, which has been linked to a variety of health problems, including obesity, hypertension, heart disease, diabetes, irritable bowel syndrome (IBS), attention and memory problems, hyperactivity, anxiety, and depression. Every month a new study comes out adding to the list of dangers posed by consuming sugar and its cousins, high-fructose corn syrup, maltose, and dextrose. Despite the risks, we continue to eat sugar because it is so addictive.
In fact, sugar meets all the criteria for an addictive substance:
- It stimulates release of neurotransmitters in the brain, such as dopamine and serotonin, in a manner similar to alcohol, cocaine, and other drugs of abuse.
- People eat it compulsively, despite negative consequences and the intention to stop.
- With continued use, people develop a tolerance to its effects.
- Heavy sugar consumers have trouble functioning without it.
- When consumption ceases, withdrawal symptoms occur.
Breaking free from a dependency on sugar is easier said than done. Because the roots of sugar addiction are both physical and emotional, you need a combination of physical and psychological approaches. The less you eat sugar, the less you will crave it. If you get withdrawal symptoms, know they will only last a few days and then you’ll feel more balanced and energetic than ever.
These 10 recommendations will make it easier to get a sugar problem under control.
1. Keep sugar and sugar products out of your house. This includes white and brown sugar, corn syrup, and maple syrup.
2. Eat enough healthy food to satisfy your hunger. Eat healthy, whole food snacks like fruit, carrots, red pepper, cherry tomatoes, dates, and dried fruit to satisfy your sweet tooth. Drink plenty of water, too. Add a little fruit juice to sweeten iced tea, carbonated water, and other sugar-free drinks. Frozen fruit, whole or pureed, makes a delicious alternative to ice cream. Once you have cleared sugar from your system, your taste buds will become more sensitive, and these whole natural foods will taste sweeter and more satisfying. If you slow down and eat mindfully, you’ll enjoy these foods even more.
3. Eat three regular meals each day that combine complex carbohydrates (vegetables, whole grains, and fruits), lean protein (poultry, fish, meat, dairy, tofu) and healthy fats (milk, cheese, omega-3′s, olive oil and other cold-pressed oils). This will help you maintain a steady blood sugar level throughout the day and reduce your sugar cravings. Eating a diet high in fiber also helps to reduce sugar cravings.
4. Take a multivitamin and mineral supplement. Chromium picolinate and l-glutamine help to reduce cravings for some people.
5. When you go out, make sure you are not ravenously hungry, especially if sugary sweets will be the only food available. Bring your own healthy snacks with you, or eat before going out.
6. Get regular exercise, plenty of sunlight, and adequate sleep to reduce sugar cravings.
7. Learn to identify and manage cravings that are not a result of physical hunger, but instead are rooted in stress or anxiety. Develop alternative ways of managing stress: Take a walk, call a friend, read a book, play with your pet, watch a movie. Breathe, meditate, listen to music, or take a hot bath to activate your body’s relaxation response. Relaxation helps to balance your blood sugar and reduce cravings.
8. If you have turned to sugar to deal with uncomfortable feelings, learn to identify the specific feelings and respond appropriately to them. If you are tired, take a break or rest, rather than trying to persevere in the face of fatigue. If you are bored, find something stimulating to do. If you are lonely, reach out to a friend. Overcoming your sugar addiction involves really paying attention to what you are feeling, and giving yourself what you really need instead of using sugar as a substitute.
9. If you do overindulge in sugar, acknowledge that you slipped, and get back on track as soon as possible. Let go of the guilt and shame. Eating sugar is unhealthy, but it’s not a sin. As with other addictions, it doesn’t matter if you need multiple attempts to quit, just that you keep trying until it sticks.
10. Be kind to yourself. To end the struggle with sugar, learn to nourish your body well and respond compassionately to your own feelings. The best sugar substitute is genuine self-acceptance.
Jeffrey Rossman, Ph.D., is a Rodale.com advisor and director of life management at Canyon Ranch in Lenox, MA. His column, “Mind-Body-Mood Advisor,” appears weekly on Rodale.com.


